FROM WHERE TO WHAT: A NEUROANATOMICALLY BASED EVOLUTIONARY MODEL OF THE EMERGENCE OF SPEECH IN HUMANS [VERSION 2; REFEREES: 1 APPROVED, 2 APPROVED WITH RESERVATIONS]

In the brain of primates, the auditory cortex connects with the frontal lobe via the temporal pole (auditory ventral stream; AVS) and via the inferior parietal lobe (auditory dorsal stream; ADS).The AVS is responsible for sound recognition, and the ADS for sound-localization, voice detection and integration of calls with faces.I propose that the pr

Within the framework of limit design applied to Microwave Door Frame masonry structures, this paper aims at analyzing the different behavior of a pavilion dome according to the adopted construction and reinforcement technologies.By using the static theorem applied to the dome discretized in rigid macro-blocks of variable shape aligned along paralle

Background Recent impressive advances in cancer immunotherapy have been largely derived from cellular immunity.The role of humoral immunity in carcinogenesis has been less understood.Based on our previous observations we hypothesize that an immunoglobulin subtype IgG4 plays an essential role in cancer immune evasion.Methods The distribution, abunda

Abstract Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is closely associated with various malignancies.Considering the complex life cycle of EBV, developing vaccines targeting key entry glycoproteins to elicit robust and durable adaptive immune responses may provide better protection.EBV gHgL-, gB- and gp42-specific antibod